Site Solutions

OnCore

Clinical Trial Management System (CTMS)

OnCore by Advarra is the most widely adopted CTMS among leading academic medical centers, NCI-designated cancer centers, hospitals, and health systems. It serves as the backbone for managing studies across the lifecycle, including protocol setup and activation, participant tracking, financial oversight, and reporting.

Why Organizations Choose OnCore CTMS?

Integrated Financial Workflows and Billing Compliance

Strengthen financial performance and billing compliance through seamless integrations with billing systems and tools, such as general ledger (GL) or enterprise resource planning (ERP) system, that support critical workflows, including budgeting, invoicing, and receivables.

Real-time EMR data exchange with Epic and Cerner

Connect subject, protocol, and billing data through deep EMR integration with widely used EMR systems, including Epic and Cerner.

Advanced Analytics and Decision Insights

Unlock actionable insights on study performance, enrollment, and revenue through OnCore Analytics across study, participant, and financial data, along with standardized reporting capabilities, such as NCI reporting, to support informed clinical and operational decision-making.

Specialized Study Management Tools for Complex Trial Needs

Leverage robust capabilities such as biospecimen management (BSM), protocol review management system (ePRMS), registry management, and Advarra EDC technology for investigator-initiated trials (IITs).

Robust Functionality and Reporting for NCI-Designated Cancer Centers

Take advantage of tailored capabilities to meet Cancer Center Support Grant (CCSG) and Clinical and Translational Science Award (CTSA) requirements, Clinical and Translational Science Institute (CTSI) programs, and children’s hospitals, including internal auditing, data safety oversight, automated data table reporting, Protocol Review and Monitoring Committee (PRMC) workflows, and more.

The premier partner for academic medical centers and cancer centers

+

active studies managed

+

live integrations with enterprise systems

%

of top NIH-funded institutions

Streamlining Clinical Trial Operations and Increasing Revenue with OnCore

Marilyn Larson, Associate Director of Administration at the Medical College of Wisconsin Cancer Center, emphasizes that the value of OnCore comes from its ability to streamline trial operations, improve efficiency through Epic integration, and support more accurate study tracking and revenue capture.

Centralizing Operational Data through the Flexibility of OnCore

Discover how OnCore has helped institutions manage clinical trial information based on their needs. Ashlee Lang, director of the Office of Clinical Research, speaks to the value of being able to centralize all clinical trial operational data in one place and the importance of flexibility with a CTMS to be able to tailor to the needs of an organization.

Building Community and Collaboration with an Innovative Technology Partner

Emma Barkman, director of Regulatory Affairs at the University of Maryland Greenebaum Comprehensive Cancer Center, emphasizes that the value of partnering with Advarra comes from the strength of OnCore and the supportive community it fosters.

Trusted by clinical research organizations

“The interface between OnCore and Epic has put us in a much better place in terms of billing compliance. I don’t think we could be more compliant right now.”

Kelly Anastasio Sr. Associate Director, Clinical Trials Operations, Yale Center for Clinical Investigation

Read the case study

Connect your clinical research technology

eReg + eConsent

Save money, improve efficiency, and ensure regulatory compliance across your organization with a 21 CFR Part 11-compliant system designed to adapt to regulatory management and eConsent workflows for any size research site.

eSource + EDC

Enable your staff to easily capture and manage data, facilitate remote workflows, and eliminate duplicative processes, all in a 21 CFR Part 11-compliant eSource + EDC system integrated with Clinical Conductor CTMS.

Integrating throughout the enterprise

OnCore also integrates with other Advarra solutions and enterprise systems your organization relies on, connecting research workflows and data across your organization.

eIRB (via OnCore API)

CRPC Billing Grid (EMR)

Demographics (EMR)

Subject/Protocol Information (EMR)

General ledger

OnCore Analytics

Advarra Payments

OnCore_sidebar

Business intelligence for
your clinical trial operations

Surface the right data to improve your operational strategies with Advarra Analytics.

Identify trends, spot problem areas, and ensure your organization is moving forward with the most accurate information available. Sophisticated, easy-to-use data visualizations and seamless integration with OnCore provide you with actionable insights related to accrual, study activation, effort, and more.

Frequently asked questions

How do I know if OnCore is right for my organization?

OnCore typically addresses the needs of academic medical centers and cancer centers, as well as some health systems, conducting fifty to 500+ active trials. If you need functionality in areas such as clinical research management, billing compliance, biospecimen management, or financial management, OnCore may be a good fit.

How much does OnCore cost?

The OnCore licensing fee is dependent upon your licensed modules and your volume of protocols. An annual subscription fee covers license, maintenance, support, and upgrades. Contact our sales team to learn more.

Can OnCore integrate with my internal systems?

OnCore offers robust integration with EMR systems, including RPE integration for protocol and subject information, and IHE CRPC billing designations to enhance billing compliance. OnCore also provides an API to interface with your applications, including your eIRB system.

What modules are included with an OnCore subscription?

An enterprise OnCore license includes clinical research management, billing compliance, and numerous integrations. Additional modules such as biospecimen management are licensed separately.

Featured content

Driving Site Efficiency and Visibility Using a CTMS

Driving Site Efficiency and Visibility Using a CTMS

This eBook outlines several challenges you may face as you conduct research, and how a clinical trial management system (CTMS) can address them.

4 Key Integrations for Your Clinical Trial Management System

4 Key Integrations for Your Clinical Trial Management System

In this blog are some key CTMS integrations — using systems your institution has likely implemented — your team can use to streamline research operations.

4 Questions to Ask CTMS Vendors

4 Questions to Ask CTMS Vendors

Here are four questions to ask during the CTMS selection process to offer more insight into your future success with the selected vendor.

Beginner’s Guide to Clinical Trial Management Systems

Beginner’s Guide to Clinical Trial Management Systems

From the largest research centers to the smallest, sites now recognize that a clinical trial management system (CTMS) can be configured to their needs and can bring powerful efficiencies insights, and compliance to their day-to-day operations.

Collaborate and Drive Clinical Research Forward

Advarra welcomes technology customers to a robust network of the nation’s leading clinical research professionals sharing best practices and addressing current challenges. The Onsemble Community allows researchers to collaborate with colleagues while shaping the industry and the technologies we use every day. When we work together, we can all move clinical research forward.