REVIEWS
EAC Services
Endpoint Adjudication Committee (EAC)
Tailored adjudication services to help you capture clear, actionable data that drive impactful decisions and support regulatory approvals, which builds credibility with regulators, sponsors, and healthcare providers.
Independent Clinical Endpoint Adjudication
No matter the therapeutic area, study design, geographic region, or other unique study considerations — our experienced team and flexible processes can scale to support any biopharma or device project.
We work with you to identify the right medical experts for your trial while operating independently to eliminate any appearance of conflict.
Enhanced Data Integrity
Centralized and independent oversight reduces variability in endpoint assessments, enhancing data consistency and reliability. Our well-defined adjudication workflow minimizes delays, facilitating timely endpoint assessment without compromising quality.
Improved Independence
Whether the trial requires just one independent medical expert or multiple EAC members, endpoint adjudication must be independent of the sponsor per U.S. FDA and EU EMA guidelines. Ensure independence when you separate clinical trial oversight from trial execution and conduct.
Unmatched Expertise
Leverage Advarra’s worldwide network of over 1,500 medical experts, biostatisticians, and other clinical professionals. Our EACs are comprised of world-leading experts with the technical prowess to evaluate the most challenging endpoints and the experience to understand the various comorbidities, and confounding variables present in complex clinical trials.
Optimized Compliance
Save time and resources with truly integrated review services. While the review committees are separate, Advarra coordinates all the institutional review board (IRB), institutional biosafety committee (IBC), data monitoring committee (DMC), and EAC reviews to reduce delays and ensure consistency.
Featured Content
Technology-enabled Reviews
Improve compliance and reduce administrative burden with the most integrated reviews solutions in the industry. All of our review services are supported by best-in-class technology platforms, which provide clients with real-time information on review timelines and deliverables. Advarra’s platform for safety oversight administration and reporting (SOAR) provides connectivity and role-based transparency for all parties involved in an Advarra-administered EAC.
Compatible with any electronic data capture (EDC) or similar clinical records system and configurable to handle sophisticated adjudication determinations with parallel, sequential, and other complex determination workflow types.
Advarra’s reviews technologies integrate easily into a sponsor’s electronic trial master file (eTMF) platforms and site systems via API.
Frequently Asked Questions
Explore our comprehensive FAQ page for detailed answers to questions we get around IRB, IBC, DMC, and EAC services.